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Paper Id: IJCIRAS1165
Title: LIPID BASED NANO-PARTICLES: SLN/NLCS – FORMULATION TECHNIQUES, ITS EVALUATION AND APPLICATIONS
Published in: International Journal Of Creative and Innovative Research In All Studies
Publisher: IJCIRAS
ISSN: 2581-5334
Volume / Issue: Volume 1 Issue 11
Pages: 12
Published On: 4/18/2019 1:36:14 AM      (MM/dd/yyyy)
Main Author Details
Name: Priyanka Balkrishna Shinde
Institute: SES’S R.C. Patel Institute of Pharmaceutical Education and Research, Shirpur
Co - Author Details
Author Name Author Institute
Deshmukh Shweta Gunvantrao SES’S R.C. Patel Institute of Pharmaceutical Education and Research, Shirpur
Suryawanshi Meghraj Vivekanand Cerelia Nutritech Pvt. Ltd. New Delhi
Abstract
Research Area: Pharmacy, Pharmacology & theraputics
KeyWord: SLN, NLCs, colloidal drug carriers, homogenization, characterization, application.
Abstract: This review represents the usage of SLN and NLCs regarding their advantages, formulation methodology, characterization and applications. If suitably investigated, SLNs/NLCS may open new prospects in therapy of complex diseases. Solid lipid nanoparticles (SLN) were formulated at the emergence of the 1990s as a replaced carrier system to emulsions, liposomes and polymeric nanoparticles. SLN are aqueous colloidal dispersions, the matrix of which consists of solid biodegradable lipids. Nanostructured lipid carriers (NLCs) are drug-delivery systems consists of both solid and liquid lipids as a core matrix. It was shown that NLCs has some advantages for drug therapy over conventional carriers, including higher solubility, the ability to enhance storage stability, improved permeability and bioavailability, reduced adverse effect, prolonged half-life, and tissue-targeted delivery. SLN and NLCs are manufactured by techniques like high pressure homogenization, solvent diffusion method ultrasonication, solvent emulsification etc. Both SLN/NLCs have applications in for parenteral, nasal, respiratory, ocular, rectal, and topical, in chemotherapy, etc.
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IEEE
Priyanka Balkrishna Shinde, Deshmukh Shweta Gunvantrao, Suryawanshi Meghraj Vivekanand, "Lipid Based Nano-particles: SLN/NLCs – Formulation Techniques, its evaluation and Applications", International Journal Of Creative and Innovative Research In All Studies, vol. 1, no. 11, pp. 20-31, 2019.
MLA Priyanka Balkrishna Shinde, Deshmukh Shweta Gunvantrao, Suryawanshi Meghraj Vivekanand "Lipid Based Nano-particles: SLN/NLCs – Formulation Techniques, its evaluation and Applications." International Journal Of Creative and Innovative Research In All Studies, vol 1, no. 11, 2019, pp. 20-31.
APA Priyanka Balkrishna Shinde, Deshmukh Shweta Gunvantrao, Suryawanshi Meghraj Vivekanand (2019). Lipid Based Nano-particles: SLN/NLCs – Formulation Techniques, its evaluation and Applications. International Journal Of Creative and Innovative Research In All Studies, 1(11), 20-31.
Lipid Based Nano-particles: SLN/NLCs – Formulation Techniques, its evaluation and Applications
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